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These trials confirmed clinically major pharmacokinetic interactions [seven] characterised by a minimize within the clearance with the anticancer drug and hence enhanced exposure. The interpretation of subsequent stage II and III clinical trials was challenging as it was impossible to administer the identical dose of chemotherapy from the existence

antineoplastic exercise when this compound was to start with claimed, utilizing the P-388 murine lymphocytic leukemia model (T/C caThe solubility of cepharanthine in injections is minimal and its use is limited. Pulmonary drug supply is restricted from the solubility of cepharanthine and necessitates consideration to formulation style and design. N